Can caffeine protect against Alzheimers?

[Dennis]

Re: Can caffeine protect against Alzheimers?

http://coffeesnobs.com.au/YaBB.pl?num=1191411894/6#6

They must have forgotten that this has already been researched. ;D

[Dimal]

Re: Can caffeine protect against Alzheimers?

;D ;D

[coastal_coffee]

Re: Can caffeine protect against Alzheimers?

So does this mean we should be worried.

WHAT IF WE WERE NOT DRINKING COFFEE,

Would we be able to find the board without bookmarks...................


and what about the unsaved login details.

Or worse , Why are we here?

[TEPIN]

Coffee And Alzheimers

http://news.bbc.co.uk/2/hi/health/8132122.stm

[TEPIN]

Re: Can caffeine protect against Alzheimers?

Well Javaphile Phuck Me I forget reading your post about this, note to self "drink more Coffee"..

[dsgfh]

Re: Can caffeine protect against Alzheimers?

Saw this on the news this morning. Couldnt help but be amused at the shock in their voices that you would have to consume the equivalent of three (yes, THREE) espressos every day to get those caffeine levels. If they only knew...

On the other hand, I shuddered when I saw the "espresso" pour.

[CoffeeFiend]

Re: Can caffeine protect against Alzheimers?

I dont know that much about Alzheimers but this makes sense to me. I know that once you access certain neural pathways, they are much easier to RE-access after that again and again. Coffee as a stimulant does help me focus and concentrate more and increases my memory, but even when I dont get any coffee for a day or two I can still focus better than I used to be able to before I ever drank coffee.

I had the same experience with the body building supplement creatine, which also works as a smart drug. I have some insomnia problems but creatine took away the symptoms of grogginess and being a zombie. Even after I stopped taking it for like a year, my symptoms are still very mild because my brain learned how to access those neural pathways.

Maybe Im rambling but the point is that it makes sense, at least to me!  

[paulstainsby62]

Re: Can caffeine protect against Alzheimers?

Better tell my dear old Mum about this she is terrified that she will get Alzheimers as her mother got it early. Might be an excuse to take the coffee machine when I go to visit her in Bunbeburg at Chrissy

[redzone121]

Re: Can caffeine protect against Alzheimers?

I remember reading a thread on ........

[Thundergod]

Re: Can caffeine protect against Alzheimers?

http://www.youtube.com/watch?v=VYCB_VxMgbY

[russellb]

More reasons for coffee

Hi all

A recent article in the Journal of Alzheimers Disease (Volume 30, Number 3, June 2012 Pages 559-572) suggests that intake of 3-5 cups of coffee daily may decrease the risk of progression of mild cognitive impairment to dementia.  The evidence is observational only on a fairly small group and not well controlled, but suggestive at present:

Quoted from Medscape:

"The new case-control study included 2 cohorts of 124 participants in a Florida Alzheimers Disease Research Center study of persons aged 65 years and older. All participants had undergone a battery of baseline neurologic assessments and cognitive tests and were categorized as normal, MCI, or dementia. As well, researchers had access to fasting blood samples taken at baseline.

Over the next 2 to 4 years, researchers annually reassessed the cognition of the participants. They separated the participants into 5 groups: (1) initially normal and remained normal, (2) initially normal but converted to MCI, (3) initially MCI and remained so, (4) initially MCI but converted to dementia, and (5) initially dementia and remained so.

Analysis of plasma caffeine levels from the initial visit showed significantly lower caffeine levels in participants with MCI relative to the normal group (P < .03). Caffeine levels were also lower in participants with dementia than in those with normal cognition, but this association did not reach statistical significance (P < .07).

There was a 26% lower plasma level of caffeine in normal persons who converted to MCI over the course of the study compared with those who remained normal, but this was not significant because of considerable variability in caffeine levels among individuals in both of these subgroups.

However, 11 patients with MCI who progressed to dementia had plasma caffeine levels that were 51% below levels at study initiation vs those with MCI who remained MCI (P < .02).

None of the MCI participants who converted to dementia had initial caffeine levels above 1200 ng/mL while half of those with stable MCI had higher levels. Baseline plasma caffeine levels greater than 1200 ng/mL in MCI patients were associated with a 100% chance of avoiding progression to dementia during the 2- to 4-year follow-up.

That 1200-ng/mL level appears to be an important threshold, said Dr. Arendash. The amount of coffee needed to reach this critical level appears to be 3 to 5 cups of daily, with a target of 5 cups or 500 mg of caffeine. Those previous AD mouse studies showed that 1 to 2 cups, or between 100 and 200 mg of caffeine (which is what typical Americans drink daily), was not enough to ward off dementia, he said. Its not known whether its necessary to spread those 5 cups throughout the day, he added.

Its important to remember, though, that half of the patients with stable MCI in the study who had caffeine levels below 1200 ng/mL also didnt progress to dementia. Clearly, other factors play a role. Such factors probably include the level of cognitive and physical activity, the presence of hypertension, and antioxidant intake, especially from fruits and vegetables, said Dr. Arendash."

Looks promising, but really needs good interventional studies on a bigger group and probably a longer time to confirm. In the meantime if you needed an excuse for another cup, there it is, especially if you are a mouse.

Russell

[Rocky]

My insurance is that I am teaching my son (who it looks like may be around for the long run) to use my machine and the instruction is that currently I make coffee for him but later on he will make coffee for me. "You remember Dad, you REALLY like coffee... here try some".

[Danieln]

This is a great motivation for me to drink more coffee :-)

[Caneurysm]

I don't even know that caffeine can protect a person from Alzheimer's disease. I am not aware of that but it's awesome to know that caffeine has its own benefits to human, but I guess over consuming of caffeine is also dangerous.

What's TRULY dangerous is getting in my way when I have under consumed my daily caffeine intake.

[Barry_Duncan]

Many drugs have side effects. I drink 3 to 5 coffees a day. If the side effect of my coffee drinking habit may help maintain my mental health then that is great. I will drink to that.

Barry